|
KMID : 0388420040140010077
|
|
Konkuk Journal of Medical Sciences
2004 Volume.14 No. 1 p.77 ~ p.90
|
|
|
Estimation of Population Attributable Risk Percent (PARP) and Cumulative Risk by Exposure Fraction of Breast Cancer Risk Factor
|
|
Park Sue-Kyung
|
|
|
Abstract
|
|
|
|
To establish the prevention strategy breast cancer in Chungcheongbuk-do female population, we estimated the population attributable risk percent (PARP) according to population exposure fraction of risk factors and the cumulative risk until 64 years, using previous data in Korean. The cumulative risks until 64 years old for breast cancer were calculated by the age-specific incidence rate (Yoo et al., 1998; Appendix 2), the population exposure fraction of breast cancer (Appendix 3) and the odds ratios of risk factors in hospital breast cancer case-control study (Yoo et al 1998; Appendix 4), through the formula suggested in Kleinbaum et al., (1982) and IARC (1992). The PARP by exposure fraction status were calculated by previous data of the odds ratios and population exposure fraction of breast cancer, through the formula suggested in Cole and Macmahon (1971) and Kelsey et al. (1986). And protective fraction percent (PFP) was calculated through the formula suggested in Miettinen (1974). Based on three criteria (1. PARP > ±10%, 2. the significance of 95% confidence interval of odds ratios, 3. cumulative risk ratio (CRR)>1.5 or CRR<0.7), we suggest that high risk group by breast cancer prevention strategy in Korea should be selected as the women with BMI>26 kg/m2, regular menstruation, & alcohol drinking, and parous women having over and at 2 children.
|
|
|
KEYWORD
|
|
|
population attributable risk percent, cumulative risk, breast neoplasms, high risk group, Korea
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|